人才队伍
项目副研究员
翁婷,2015年7月在新加坡南洋理工大学获博士学位,随后先后在新加坡国立大学Mechanobiology Institute和新加坡南洋理工大学从事博士后研究,主要开展调控肿瘤细胞凋亡以及癌症发生发展相关信号通路研究,2018年6月加入中国科学院重庆绿色智能技术研究院从事纳米孔测序及检测技术开发研究。2019年入选“西部之光”青年人才B类项目,2023年入选“中国科学院青年创新促进会”。
精准医疗单分子诊断技术研究中心
[1] Weng T, Koh C-G. POPX2 phosphatase regulates apoptosis through the TAK1-IKK-NF- B pathway[J]. Cell Death & Disease, 2017, 8(9): e3051–e3051. (一作)
[2] Zhang S, Weng T, Cheruba E, Guo T, Chan H, Sze S K, Koh C-G. Phosphatase POPX2 Exhibits Dual Regulatory Functions in Cancer Metastasis[J]. Journal of Proteome Research, 2017, 16(2): 698–711. (二作)
[3] Ou S, Tan M-H*, Weng T*, Li H, Koh C-G. LIM kinase1 regulates mitotic centrosome integrity via its activity on dynein light intermediate chains[J]. Open Biology, 2018, 8(6): 170202. (共二作)
[4] Yan H*, Weng T*, Zhu L, Tang P, Zhang Z, Zhang P, Wang D, Lu Z. Central Limit Theorem-Based Analysis Method for MicroRNA Detection with Solid-State Nanopores[J]. ACS Applied Bio Materials, 2021, 4(8): 6394–6403. (共一作)
[5] Tian R*, Weng T*, Chen S, Wu J, Yin B, Ma W, Liang L, Xie W, Wang Y, Zeng X, Yin Y, Wang D. DNA nanostructure-assisted detection of carcinoembryonic antigen with a solid-state nanopore[J]. Bioelectrochemistry, 2023, 149: 108284. (共一作)
[6] Djebbi K, Shi B, Weng T, Bahri M, Elaguech M A, Liu J, Tlili C, Wang D. Highly Sensitive Fluorescence Assay for miRNA Detection: Investigation of the DNA Spacer Effect on the DSN Enzyme Activity toward Magnetic-Bead-Tethered Probes[J]. ACS Omega, 2022, 7(2): 2224–2233. (三作)
[7] Djebbi K, Xing J, Weng T, Bahri M, Elaguech M A, Du C, Shi B, Hu L, He S, Liao P, Tlili C, Wang D. Highly sensitive fluorescence multiplexed miRNAs biosensors for accurate clinically diagnosis lung cancer disease using LNA-modified DNA probe and DSN enzyme[J]. Analytica Chimica Acta, 2022, 1208: 339778. (三作)
[8] Tian R, Liu D, Weng T, Yin Y, Xie W, Yin B, Shi B, Tlili C, Wang D. DNA-functionalized biosensor for amplifying signal detection of DNA methyltransferase activity[J]. Journal of Electroanalytical Chemistry, 2021, 891: 115260. (三作)
[9] Yan H, Zhang Z, Weng T, Zhu L, Zhang P, Wang D, Liu Q. Recognition of Bimolecular Logic Operation Pattern Based on a Solid-State Nanopore[J]. Sensors, 2020, 21(1): 33. (三作)
1. 2021.12-2022.12,化学毒剂及其生物标志物的纳米孔检测系统研究,项目负责人
2. 2020.7-2023.6,POPX2磷酸酶调控乳腺癌细胞EMT相关机制研究,项目负责人